Flexeril – medicine acting against muscular spasms. It possesses sedative action, it is not recommended to be engaged in potentially dangerous types of activity if a person takes Flexeril. As well as in a case with narcotic analgetics, Flexeril is not recommended to take longer than seven days as in case of a long taking there can be a dependence.
Important information
Do not take Flexeril if you have used MAO inhibitors such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam) in the past 14 days. Serious, life-threatening side effects may occur if you take Flexeril before the MAO inhibitor is cleared from your body.
You should not take Flexeril if you have recently had a heart attack, or if you have a heart rhythm disorder, congestive heart failure, heart block, or an overactive thyroid.
Flexeril may cause side effects that may impair your thinking or reactions. Use caution if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which may increase some of the side effects of Flexeril.
Do not take Flexeril if you have used MAO inhibitors such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam) in the past 14 days. Serious, life-threatening side effects may occur if you take Flexeril before the MAO inhibitor is cleared from your body. Do not use Flexeril if you have recently had a heart attack, or if you have:
Heart rhythm disorders;
chronic heart failure;
Heart block; or
Overactive thyroid.
Before using Flexeril, tell your doctor if you are allergic to any medicines, or if you have:
Urinary problems;
an enlarged prostate;
glaucoma; or
Liver disease.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take Flexeril.
ULH pregnancy category B. Flexeril is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known if cyclobenzaprine passes into breast milk or may harm a nursing baby. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
How do I take Flexeril?
Take this medicine exactly as prescribed for you. Do not take Flexeril in large amounts or take it longer than recommended by your doctor. Follow the directions on the prescription label.
Take this medicine with a full glass of water.
Flexeril is only part of a complete treatment program that may also include rest, physical therapy, or other pain relief measures. Follow your doctor’s instructions.
Store Flexeril at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regular time. Do not take extra medicine to make up for the missed dose.

What happens if I overdose?
Seek medical help if you think you have used too much of this medicine. An overdose of Flexeril can be fatal.
Symptoms of an overdose may include drowsiness, fast heartbeat, tremors or shaking, slurred speech, confusion, nausea, vomiting, hallucinations (seeing things), chest pain, or seizures (convulsions).
What should be avoided?
Flexeril may cause side effects that may impair your thinking or reactions. Use caution if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which may increase some of the side effects of Flexeril. Cold or allergy medicines, narcotic pain medicines, sleeping pills, and medicines for seizures, depression, or anxiety may add to the drowsiness caused by Flexeril. Tell your doctor if you regularly use any of these medicines or any other muscle relaxant.
Flexeril side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Flexeril: hives; difficulty breathing; Swelling of the face, lips, tongue, or throat. Stop using Flexeril and contact your doctor right away if you have any of these serious side effects:
Fast, pounding, or irregular heartbeat;
Chest pain or a heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, a general bad feeling;
Sudden numbness or weakness, especially on one side of the body;
Sudden headache, confusion, problems with vision, speech, or balance;
Feeling lightheaded, fainting;
Confusion, weakness, lack of coordination;
Nausea, stomach pain, low-grade fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
Seizure (convulsions);
Unusual thoughts or behavior, hallucinations (seeing things); or
Mild bruising or bleeding, unusual weakness.
Less serious side effects of Flexeril may include:
Dry mouth or throat;
Blurred vision;
Drowsiness, dizziness, fatigue;
Loss of appetite, stomach pain, nausea;
Diarrhea, constipation, gas; or
Muscle weakness.
This is not a complete list of side effects, and others may occur. Tell your doctor about any unusual or bothersome side effect. You can report side effects to the FDA at 1-800-FDA-1088.
What other drugs will affect Flexeril?
Many drugs may interact with Flexeril. The following is a partial list. Tell your doctor if you are using:
Atropine (Donnatal, etc.), Benztropine (Cogentin), Dimenhydrinate (Dramamine), Metspopolamine (Pamine), or Scopolamine (Transderm-Scop);
A bronchodilator such as ipratroprine (Atrovent) or tiotropium (Spiriva);
Glycopyrrolate (Robinul);
Guanitidine (Ismelin);
Mepenzolate (Cantil);
Tramadol (Ultram);
Bladder or urinary drugs such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); or
Irritating bowel drugs such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Leucine, etc.) OR propantelin (Pro-Banthine).
This list is not complete and there may be other drugs that can interact with Flexeril. Tell your doctor about all prescription and over the counter medications, vitamins, minerals, herbal products, and medicines prescribed by other doctors. Do not start a new medicine without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about Flexeril.